Re: JDRF Forms Partnership W/ Animas to Develop Artificial Pancreas


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Posted by DavidL on 21:33:03 2010/01/19

In Reply to: Re: JDRF Forms Partnership W/ Animas to Develop Artificial Pancreas posted by Al Gordon


>> As a person familiar with control theory, you must know that the control algorithms that needed for a closed-loop artificial pancreas are trivial compared to the challenge of a stable, reliable, redundant, power-sipping, continuous glucose sensor. Until such a sensor exists and has demonstrated its long-term stability (in absolute terms, not just rate-of-change), then there is no need to waste a dollar developing control algorithms. Once such a sensor exists, then the control software will be up and running within weeks.

We've had some experience with Minimed's CGM, and we've been pleased with it's accuracy. We weren't put-off by the need for a few periodic BGs to keep it on track. I understand Dexcom is similar. We only used CGM open-loop to optimize pump parameters: basils and carb. ratios. I wouldn't describe closing the loop as trivial, but it's not a big reach either. Naturally, I prefer a super reliable implanted sensor with redundancies and very long life, but I wouldn't want to insist on such a requirement for version 1.0. This treatment could hold complications off while we wait for a cure. IMO, a cure delayed is a cure denied; I don't want to end up with a cured daughter who's lost her eyesight.

I'm no fan of a market who's only incentive is profit where human suffering is involved. However, I won't turn away from a closed loop system (we can afford) no matter where the development funds came from and no matter how greedy the suppliers happen to be.

We should push and hope for a cure, but we shouldn't put off improved treatment while we wait; history tells us we may be waiting a while.

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