Re: New Diabetes Encapsulation Web Site
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Posted by Jay on 18:36:06 2009/06/30
In Reply to:
Re: New Diabetes Encapsulation Web Site posted by Steve R
Hi Scott,
With respect to your article on glucose metabolism in mice vs. humans I posted the following comment/question, but I thought I'd post it here as well, as I'm flabbergasted by your description of glucose mediated glucose uptake in mice/humans, which I'd never heard of and which has pretty devastating consequences for mouse research:
Hi Scott,
This was a great article, and it explained something that I had no appreciation of prior to reading this -- the phenomenon of glucose mediated glucose uptake. I had no idea, for instance, that mice did not directly require insulin for glucose uptake...that's incredible. I wish somebody had told me that sooner, as I've posted for years on the islet foundation's forum about mouse models etc. If this is true then what is the point of doing research on a mouse at all?? Is this a widely accepted theory of glucose metabolism?
Jay.
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