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Encelle - A Novel Approach...

In any field of research, progress occurs in many different ways. In pursuing islet xenotransplantation as a cure for diabetes, each research team applies and tests certain unique principals and practices. As the world learns which approaches work and which do not, our knowledge grows and we get closer to our goal. Without such diversity, we cannot have trial and error, the basis for all human progress. One company, with a highly motivated founder and superb team of scientists and engineers, offers an approach to our mission which stands apart from the mainstream.

Encelle, Inc., a young company in Greenville, North Carolina, is a fascinating new entry in the world of encapsulated islet xenotransplantation. They appear to be at odds with all the conventional wisdom in the field today, and actual results are preliminary. However, their approach produces a bioartificial pancreas - Encellin XP - that is much closer to the environment and behavior of a normal pancreas.

The founder is Dr. Anton-Lewis Usala, a Pediatric Endocrinologist and Clinical Associate Professor of Pediatrics at East Carolina University, with a strong background in polymer chemistry (His father was a polymer chemist at Dupont, and an inventor of Lucite). Perhaps the most compelling aspect of Encelle is that Dr. Usala has had type 1 diabetes since age one, and at 40 years of age, has non-diabetic glycated hemoglobin values, no retinopathy, and is in good health (using multiple daily injections of insulin since age 10). The source of his motivation is self-evident.

The following is a list of all the things that Encelle is doing differently from current conventional wisdom in the field of islet xenotransplantation, and the benefits which the company claims:


Read about the visit to Encelle on May 15/16 by a scientific and charitable delegation
 Raleigh News & Observer - Dec 23 1998 - Encelle testing diabetes remedy
 Diabetes Mall - Dec 26, 1998 - Encelle Receives Research Funding For Beta Cell Transplants
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